“Research is to see what everybody else has seen, and to think what no one else has thought "

Publications in Prestigious High Impact Factor Journals

1. the lancet hematology - if 19.5

2. Oral Oncology - IF 4.9

3. journal of american dental association - if 3.8

4. PLOS ONE - IF 3.8

5. Oral Diseases -IF 3.6

6. Journal of Oral Pathology & Medicine - IF 3.5

7. Medical hypothesis - if 3

8. Archives of Oral Biology- IF 2.8

9. Head and Neck Pathology - IF 2.6

10. Oral Surgery Oral Medicine Oral Pathology Oral Radiology OOOO - IF 2.5

11. Asian Pacific Journal of Cancer Prevention- IF 2.267

Publications 2025
1. Molecular profiling of oral epithelial dysplasia and oral squamous cell carcinoma using next generation sequencing, RP Krishnan, D Pandiar, P Ramani, S Jayaraman, Journal of stomatology, oral and maxillofacial surgery 126 (4), 102120:142025

2. Vitamin D3-Infused Nanogel: A Promising Strategy for Combating Oral Mucositis with Antioxidant, Anti-inflammatory, and Anticancer Benefits: An In vitro Study. T Agarwal, S Sagar, G Jeyaraj, M Surya, P Ramani. Journal of Maxillofacial and Oral Surgery, 1-8, 2025

3. Waterpipe smoke condensate activates the oncogenes and promotes epithelial–mesenchymal transition to cause oral cancer, P Prasad, G Sriram, B Kannan, M Jaber, AMB Khair, A Ramasubramanian, ...Odontology, 1-10: 2025

4. Waterpipe smoking as deregulator of RNA m6A modification and promotor of epithelial-mesenchymal transition to cause oral cancer., P Prasad, B Kannan, A Ramasubramanian, P Ramani, P Arumugam, Journal of Clinical Oncology 43 (16_suppl), e18059-e18059, 2025

5. Evaluation of Stromal Mucin Expression in Oral Submucous Fibrosis and Its Progression to Oral Squamous Cell Carcinoma, A Sujitha, P Ramani, SK Nair. Journal of Stomatology Oral and Maxillofacial Surgery, 102408:2025

6. Saliva-based biomarkers and salivary microbiome in psoriasis: A growing area of research and its relevance, S Singh, P Ramani, ND Jaykumar, B Sharma, RKK Kaur, RK Sharma, ...Microbes and Infectious Diseases, 2025

7. Efficacy of alternative agents to Carnoy’s solution in the prevention of recurrence in odontogenic keratocyst: a systematic review and meta-analysis, S Aarthi, M Yuwanati, P Ramani, G Sukumaran

Evidence-Based Dentistry, 1-7:2025

8. Primordial Odontogenic Tumor Associated with Impacted Supernumerary Tooth: First Case Report and an Updated Review of Literature, S Sebastian, SP Selvam, P Ramani. Journal of Maxillofacial and Oral Surgery, 1-11:2025

9. In silico assessment of the anticancer effects of tecomaquinone I, brevilin A, erybraedin A, evodiamine, and sumadain C in oral squamous cell carcinoma, M Muthusamy, P Ramani, M Doble, R Ramadoss. Eurasian Journal of Medicine and Oncology, 7073: 2025

10. Association of insulin receptor substrate 1 expression in the prognosis of head and neck squamous cell carcinoma: a systematic review and meta-analysis, D Prabhuvenkatesh, P Ramani, MB Yuwanati, G Sukumaran, Oncology 103 (3), 253-26332025

11. Salivary cytokines as a biomarker for diagnosis, prognosis and treatment of oral squamous cell carcinoma: A systematic review. G Rengasamy, HS Kasirajan, VP Veeraraghavan, P Ramani, G Cervino, ...biomarkers 14, 33,2025

12. Exploring the predictive power of antinuclear antibodies and Rheumatoid factor correlations in anticipating therapeutic outcomes for female patients with coexisting Sjögren's …AK Pandarathodiyil, P Ramani, B Sivapathasundharam, R Ramadoss, Journal of Oral Biology and Craniofacial Research 15 (2), 288-296,2025

13. Insulin receptor substrate 1 (IRS 1) serum levels in patients with Oral Squamous Cell Carcinoma. D Prabhuvenkatesh, K Ramalingam, P Ramani, S Jayaram. Oral Oncology Reports 13, 100708:2025

14. Assessment of cancer associated fibroblasts amongst different histological variants of oral squamous cell carcinoma. RP Krishnan, D Pandiar, P Ramani, N Kannan, S Jayaraman

Oral Oncology Reports 13, 100696. 2025

15. CREATING A DIET INDUCED OBESITY ZEBRAFISH MODEL FOR ANALYSIS OF METABOLIC PROGRAMMING IN TUMORIGENESIS.V Vivekbalamithran, R Ramya, A Ramasubramanian, P Ramani. Cuestiones de Fisioterapia 54 (4), 6365-6371:2025

16. Antibacterial Activity of Ipomoea Batatas Mediated Zinc Oxide Nanoparticles Against Streptococcus Mutans. A Sakthivel, SP Selvam, RK Shanmugam, R Ramadoss, S Sundar, ...Case Studies on Holistic Medical Interventions, 286-290.2025

17. Gold Nanoparticle Enhanced TNFα Antibody Interface Using Saliva for Predicting Prognosis in OSCC. KH Shree, R Gayathri, VP Veeraraghavan, P Ramani, R Ramadoss, ...Archives of Oral Biology, 106196: 2025

18. Characterizing miR-20a-3p Expression in the Progression of Oral Squamous Cell Carcinoma. P Thomas, P Ramani, A Ramasubramanian, D Sekar. Journal of Advanced Oral Research, 23202068241307076:2025

19. Genetic analysis of Mixed Lineage Kinase domain-like pseudokinase (MLKL) in Oral Squamous Cell Carcinoma: A Comparative Evaluation between Young and Old patients. RP Krishnan, D Pandiar, S Jayaraman, P Ramani. Journal of Stomatology, Oral and Maxillofacial Surgery, 102279: 2025

20. LAWSONIA ALBA MEDIATED SYNTHESIS OF SILVER NANOPARTICLES AND ITS ANTI CARIOGENIC ACTIVITY. P Anushya, P Ramani, S Rajeshkumar. Cuestiones de Fisioterapia 54 (3), 4556-4567:2025

21. Increased preponderance of glutamatergic dysregulation in atypical facial pain. TF Fathima, R Suresh, R Ramadoss, S Sundar, SP Selvam, P Ramani, ...European Journal of Mass Spectrometry 31 (1-2), 63-69

22. Oral Surgical Site Infections and Wound Healing Associated with Silk Fibroin Sutures versus Alternative Suture Materials: A Systematic Review..KK REDDY EALLA, N KUMARI, E ROUT, V SAHU, ...Journal of Clinical & Diagnostic Research 19 (2)

23. Doxycycline-integrated silk fibroin hydrogel: preparation, characterizations, and antimicrobial assessment for biomedical applications. KKR Ealla, CS Durga, V Sahu, N Kumari, J Venkatesan, ...

BMC Oral Health 25 (1), 177

24. Assessment of various etiological factors for oral squamous cell carcinoma in non-habit patients-a cross sectional case control study. M Muthusamy, P Ramani, P Arumugam, P Rudrapathy, B Kangusamy, ...BMC Oral Health 25 (1), 62

25. Hydroxyapatite/Porous silica coating on Cp-Ti substrates for treating dental implant infections.. M Ranjan, P Ramani, S Kizhakkoottu, K Madhu. Journal of Dental Specialities 13 (1)

26. Alpha-tocopherol Levels in Predicting the Biological Behaviour of Ameloblastoma–A Comparative Study. N Ubayathulla, MR Muthusekar, P Ramani, S Kizhakkoottu, ...Annals of Maxillofacial Surgery, 10.4103

27. Idiopathic sialadenosis mimicking neoplasms: Clinical and histopathological considerations. S NishaJaisree, P Ramani, R Abilasha, BR Varun

Journal of Oral and Maxillofacial Pathology 29 (1), 145-151

28. Stromal Dominance Mediated by COL1A2 as a Deterministic Prognostic Indicator in Oral Cancer. K Nitya, R Ramadoss, PK Yadalam, P Ramani. Advances in Sports Science and Technology, 459-464

29. Prevalence of Supernumerary Teeth in Males in the Orthodontic Outpatient Population—An Institutional Study. S Dharini, N Akash, P Ramani. Advances in Sports Science and Technology, 669-674

30. Prevalence of Regressive Alterations of the Teeth among Patients with Oral Submucous Fibrosis—An Institutional Study. G Priyadharshini, AS Pavithra, P Ramani. Advances in Sports Science and Technology, 831-837

31. Assessment of Antimicrobial and Cytotoxic Activity of Azadirachta Indica and Ficus Benghalensis Herbal Formulation for Orthodontic Patients Mouthwash Preparation—And Invitro Study. NF Begum, L Reethega, R Abilasha, P Ramani, S Rajeshkumar, ...Advances in Sports Science and Technology, 930-936

32. Role of PDGFRA-Associated miR-140 in Modulating Necroptotic Proteins in Oral Squamous Cell Carcinoma: A Molecular Docking Study. RP Krishnan, D Pandiar, E Dilipan, A Inbarajan, P Ramani, S Jayaraman. Journal of International Oral Health 17 (1), 73-81

33. Preliminary Evaluation of the Antimicrobial, Anti-Inflammatory, Antioxidant, and Cytotoxic Activities of Taraxacum officinale Leaf Extract: An in vitro Study. N Fateen, A Ramasubramanian, P Ramani. Pharmacognosy Research 17 (1)

34. Efficacy of alternative agents to Carnoy’s solution in the prevention of recurrence in odontogenic keratocyst: a systematic review and meta-analysis. PRGS Samyuktha Aarthi, Monal Yuwanati. Evidence based dentistry 2025 (1), 1-5

35. Assessment of Antimicrobial Activity Against Candida albicans, Streptococcus mutans, Enterococcus faecalis and Staphylococcus aureus and Cytotoxic Effect of the Mouthwash …KR Dharini S, Gheena Sukumaran, Pratibha Ramani, Rajeshkumar Shanmugam1. Indian Journal of Dental research 35 (6), 1-5

36. Quantification of Apoptotic Bodies and Correlation of TNF-α & IL-2 Levels with Severity of Pemphigus Vulgaris. AADRADOIGA Renu Ravikumar1, Pratibha Ramani1, Gheena Sukumaran1, Abilasha ...Journal of advanced oral research 15 (2), 186-194

37. Acacia Concinna extracts mediated synthesis of Copper oxide nanoparticles against pathogenic bacteria. BP Anushya P, Gheena Sukumaran*, Suvarna. Cuestiones de fisioterapia 54 (3), 5210-522038.

38. High Expression of Myosin ⅩⅥ Predicts Poor Prognosis in Head and Neck Squamous Cell Carcinoma. KP Suryadevara, B Kannan, C Pandi, A Pandi, A Ramasubramanian, ...Middle East Journal of Cancer 16 (2), 118-126

39. CREATING A DIET INDUCED OBESITY ZEBRAFISH MODEL FOR ANALYSIS OF METABOLIC PROGRAMMING IN TUMORIGENESIS.. V Vivekbalamithran, R Ramya, A Ramasubramanian, P Ramani. Cuestiones de Fisioterapia 54 (4), 6365-6371

40. AWARENESS ABOUT THE ROLE OF CBCT IN IDENTIFICATION AMONG DENTAL STUDENTS. S Divyashri, R Abilasha, A Arthanari. Cuestiones de Fisioterapia 54 (3), 2504-2517

41. GENDER DETERMINATION USING INTERCONDYLAR DISTANCE OF MANDIBLE. A Sabaritha, R Abilasha. Cuestiones de Fisioterapia 54 (2), 1414-1425

42. Regional Variation of Inter Canine Distance in Tamil Nadu—A Tool for Gender Identification. ASR Bhonsle, R Abilasha. Advances in Sports Science and Technology, 1041-1044

43. Prevalence of Diabetes and Hypertension among the Implantology Outpatient Population Post Covid Lockdown—An Institutional Study. N Kannan, RS George, R Abilasha. Advances in Sports Science and Technology, 908-912

44. An in-vitro exploration of the antifibrotic activity of Naringenin: A potential therapeutic agent for oral submucous fibrosis management. SS Aarthi, D Pandiar, R Subramanian, RP Krishnan. Journal of Oral Biology and Craniofacial Research 15 (4), 849-857

45. Application of Modified ITBCC Criteria of Tumor Budding in Oral Squamous Cell Carcinoma and its Correlation with Clinicopathological Parameters and Overall Survival. G Thoke, D Pandiar, RP Krishnan. Indian Journal of Otolaryngology and Head & Neck Surgery, 1-7

46. Prevalence and morphometric evaluation of dilaceration in Indian Tamils: an analysis of 10,089 permanent teeth. A Mantri, D Pandiar, RP Krishnan, TN Maheswari, JP Evanjelin Oral Radiology 41 (2), 190-196

47. An ulcerated lesion on the floor of the mouth. D Pandiar, RP Krishnan. The Journal of the American Dental Association

48. Assessment of cancer associated fibroblasts amongst different histological variants of oral squamous cell carcinoma. RP Krishnan, D Pandiar, P Ramani, N Kannan, S Jayaraman. Oral Oncology Reports 13, 100696

49. A well-defined radiolucency of the mandible in a twenty-three year old female. D Pandiar, RP Krishnan. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 139 (3), 269-278

50. Comparison of Clinical Parameters, Histopathological Features and Status of Intraoperative Surgical Margins Between Recurrent and Non-Recurrent Oral Squamous Cell Carcinoma. HS Saklecha, D Pandiar, RP Krishnan. Indian Journal of Otolaryngology and Head & Neck Surgery, 1-8.

51. Genetic analysis of Mixed Lineage Kinase domain-like pseudokinase (MLKL) in Oral Squamous Cell Carcinoma: A Comparative Evaluation between Young and Old patients. RP Krishnan, D Pandiar, S Jayaraman, P Ramani. Journal of Stomatology, Oral and Maxillofacial Surgery, 102279

52. Global prevalence of pre eruptive intracoronal resorption (PEIR) of teeth: a systematic review of literature. D Gurunathan, D Pandiar, RP Krishnan. European Archives of Paediatric Dentistry, 1-8

53. Prevalence of Viruses in Odontogenic Cysts and Tumours: A systematic review of literature and meta-analysis. D Pandiar, D Gopinath, P Pavithran, RP Krishnan, JK Kumar, SK Veettil. Sultan Qaboos University Medical Journal 25 (1), 370-381

54. Role of PDGFRA-Associated miR-140 in Modulating Necroptotic Proteins in Oral Squamous Cell Carcinoma: A Molecular Docking Study. RP Krishnan, D Pandiar, E Dilipan, A Inbarajan, P Ramani, S Jayaraman. Journal of International Oral Health 17 (1), 73-81

Compendium of latest achievements

(Publications, Awards, Patents)

RESEARCH INNOVATIONS

EDIFY

Vision

To be and to be recognized for setting the standards of excellence in professional education and high quality scientific research.

Mission

Oral Pathology is the Science behind accurate histopathologic diagnosis and appropriate treatment planning. Oral Pathologists are instrumental in the confirmatory diagnosis of Oral Diseases before any intervention.

• To promote Academic Excellence,

• Widen intellectual horizons,

• Inculcate self discipline, and high ideals for the total personality development of individual

• To convert a novice into a competent professional with excellent theoretical knowledge and unsurpassed practical / clinical skills and

• To motivate interest in research activities, further education and social service.

Indicators

• Curriculum - We provide an unique curriculum with a fusion of the best global practices. Module based curriculum, Elective courses in various specialties, Excisional biopsy reporting by CAP-Protocol, Surgical pathology grossing, Routine practice of Molecular biology, Genetics and Bio-informatics, Emphasis on Microscopy, Cytopathology, Hematopathology and Clinical microbiology.

• Teaching - Learning & Evaluation - MILA- Multiple interactive learning algorithm (Small group learning), Dedicated Faculty with a zest for continuous improvement.

• Infrastructure & Learning resources - Largest number of case archives, Modern state-of-the-art library with extensive reading resources and internet facilities.

• Research & Innovations - Cutting edge research and Patents are designed to ease patient-related lab work.

• Student support and progression - First institution to offer running slides for First year PGs, Mentor-mentee system for moral support and motivation. It is our everlasting passion that has helped us train students to attain Clinical, Academic and Research excellence.

• Values & Best practices - Frozen sections within the MAXFAX building, Training with multitude of IHC and special stains, Training in forensic odontology and oral biopsies, Evidence based oral cancer care and follow-up, Community oral pathology. We believe that ultimate success would be to see our students become confident and successful professionals.

• Management - Dedicated sessions for Pathology lab administration, Routine documentation and monitoring through DIAS, Internal and External Quality Assessment of lab activities

Research Facilities

FROZEN SECTION - CRYOSTAT

The only dental college to have the facility of cryostat - table side surgical margin clearance attached to the OT - MAXFAX.

STEREOMICROSCOPy

Transdisciplinary research to view surface of dental hard tissues to analyze implant-tooth interface, restoration-tooth interface etc. in-vitro

IMMUNOHISTOCHEMISTRY

Antibody panel for carcinomas, sarcomas, lymphomas, odontogenic tumours and salivary gland neoplasms for research and diagnostic purposes.

SPECIAL STAINS

A plethora of special stains for advanced diagnostics and research purposes.

research Facilities for Cytogenetics, transcriptomics & proteomics

Nanodrop, Real time PCR, Western Blot and Chemidoc system, Nano CT, BRULAC, Cell culture setup, ELISA, Inverted microscope and Gel documentation systems.

Research Grants

MEMORANDUM OF UNDERSTANDING [MOU]

Tokushima University, Japan - collaborative research

College of Dentistry, university of phillipines - collaborative research

Madras University, India - joint educational programs

Pondicherry institute of medical sciences, India - ilC-EQAS

SANKARA NETHRALAYA, INDIA - RESEARCH COLLABORATION

“Teach them wisely, teach them for life.”

— Nanette L. Avery

Teaching Innovations

- Order of the Day

The undergraduate course is divided into several modules. Each module is completed within a stipulated time with students divided into small groups - and each group is handled by an individual faculty to ensure quality and ease the process of assessment.

The UG class of 100 students is divided into 6 batches - 16-17 student per batch and each batch is handled by an individual faculty which makes teaching and learning more personalised, more effective and aids an interactive environment. The classes are divided into a series of short lectures and activities after every lecture (10 minutes). Self learning is promoted by the activities and gamed conducted (Gamefication). Various methods employed include JIGSAW, KAHOOT, Peer led team based learning, Role play, Critical appraisal etc.

3. Research in undergraduate curriculum

Short term projects (5 every year ) in a part of the UG curriculum which includes various genres including genetic , molecular studies, clinical studies, nano particles, surveys and patents. Students are expected to do minimum of 5 projects everywhere which would be presented in the Annual Research Fiesta - STAR SUMMIT (Saveetha Transdisciplinary Annual Research Summit)

Teaching Innovations